Calculation of Initial Insulin Dosage for Diabetic Cats

The dose of Caninsulin and the interval between injections has to be tailored to suit each individual diabetic cat.

Hypoglycemia

As hypoglycemia is a major concern and to be avoided at all costs

  • The animal's body weight should be rounded down to the nearest whole kilogram
  • The calculated dose of insulin rounded down to the nearest whole unit

This helps to avoid overdosing particularly during initial stabilization.

Insulin dosage for diabetic cats

Starting dose:

  • 0.25-0.5 IU/kg body weight twice daily.

Pre-treatment blood glucose concentration is used as guidance for the calculation of initial insulin dose in cats. See table below:

Baseline blood glucose concentration
(mmol/L)
Baseline blood glucose concentration
(mg/dL)
Initial Caninsulin dose (rounded down to the nearest whole unit)
<20 mmol/L<360 mg/dL0.25 U/kg body weight1 unit
>20 mmol/L>360 mg/dL0.5 U/kg body weight*2 units

Remember to round the cat’s bodyweight down to the nearest whole kilogram and the calculated dose down to the nearest whole or half unit.

*The maximal dose should ideally not exceed 2 IU per injection in the first 2-3 weeks of treatment.

Avoid unduly high starting doses in cats, especially in overweight cats, where the ideal bodyweight should be used.

Subsequent dose adjustments should be in increments of 1IU per injection. For more information see dose adjustment.

Initial Insulin Dosage for Diabetic Cats

All cats should be weighed accurately before commencing treatment and at follow up visits.