All dogs are susceptible to diabetes but it is usually seen in middle aged to older dogs. A higher incidence is seen in entire bitches.
Breeds that appear to be at increased risk of developing diabetes mellitus include:
Pedigree analysis has apparently identified a genetic predisposition in Keeshonds and Samoyeds.

Estimates of the incidence of diabetes mellitus in dogs and cats range from 1:100 to 1:500